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Is Proton Therapy for Cancer is better than Radiotherapy or Chemotherapy ?

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This is a very difficult question to answer. Actually to discuss on this matter we need to know what is Chemotherapy ? What is Radiotherapy ? & What is Proton Therapy.  Are they similar or different ? In a word it can be said Proton Therapy is one kind of Radiation therapy , but modern & has less demerits or side effects than General Radio Therapy.  But before main discussion lets know clearly what are they , their kind / type of treatment ?

What is Chemotherapy ?

Chemotherapy is the use of any drug to treat any disease. But to most people, the word chemotherapy means drugs used for cancer treatment. It’s often shortened to “chemo.” Surgery and radiation therapy remove, kill, or damage cancer cells in a certain area, but chemo can work throughout the whole body. This means chemo can kill cancer cells that have spread (metastasized) to parts of the body far away from the original (primary) tumor. [ Source – cancer.org ]

What is Radiotherapy ?

Radiation therapy (also called radiotherapy) is a cancer treatment that uses high doses of radiation to kill cancer cells and shrink tumors. At low doses, radiation is used in x-rays to see inside your body, as with x-rays of your teeth or broken bones. [ cancer.org ]

Radiation therapy or radiotherapy, often abbreviated RT, RTx, or XRT, is therapy using ionizing radiation, generally as part of cancer treatment to control or kill malignant cells and normally delivered by a linear accelerator. [ wikipedia ]

Now What is Proton Therapy ?

Proton therapy is a type of radiation therapy — a treatment that uses high-energy beams to treat tumors. Radiation therapy using X-rays has long been used to treat cancers and noncancerous (benign) tumors. [ mayoclinic.org ]

In the field of medical procedures, proton therapy, or proton radiotherapy, is a type of particle therapy that uses a beam of protons to irradiate diseased tissue, most often in the treatment of cancer.

Major difference between General Radiotherapy & Proton Therapy :

Topic

Radiotherapy

Proton Therapy

Beam type

X-ray or Photon Proton

Damage

Not only targeted Tumor, But also nearby healthy tissues Only targeted Tumor

Accuracy

Damage nearby cell More accurate, sub-milimeter accuracy

Side Effects

More . as it damage more nearby healthy tissue Less

Recovery

Slowly Faster

Costing of treatment

Not too high / Low cost Higher costing / Expensive

Success 

Unable to solve complex tumors Can remove/ destroy most complex Tumors

Exponential Energization

Less than Proton Protons carry a charge and mass that is typically higher than photons used in conventional radiology.

Delivers/ Depend

Photon treatments depend on multiplying the number of beam incidences. Proton therapy delivers high-energy radiation doses directly to the tumour.

Picture

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Behind Tumour / Accuracy

Radiation behind tumour Little to no radiation behind the tumour

So it can be said Proton Therapy is much better solution for cancer treatment / Tumor Treatment Than Photon Therapy or General Radiation Therapy. Though it is costly Treatment , but it can helps you much better than General  Radiation Therapy.

Cost of Treatment :

Its just a Raf cost Table , not same for everyone/ or for all type of tumor Treatment

Cost for General Radiation Therapy

Cost for Proton Therapy

If to cure a tumor cost by this Therapy –

10,000 USD ( United States Dollar )

Than it would cost 30,000 to 40,000 USD

Where to go for Proton Treatment ? / Proton Therapy Centers

( Outside USA  LIST )

Institution Maximum energy (MeV) Year of first treatment Location
Paul Scherrer Institute 250 1984 Villigen, Switzerland
Clatterbridge Cancer Centre NHS Foundation Trust, low-energy for ocular 62 1989 Liverpool, United Kingdom
Centre de protonthérapie de l’Institut Curie 235 1991 Orsay, France
Centre Antoine Lacassagne 63 1991 Nice, France
Research Center for Charged Particle Therapy 350-400 1994 Chiba, Japan
TRIUMF 74 1995 Vancouver, Canada
Helmholtz-Zentrum Berlin 72 1998 Berlin, Germany
Proton Medical Research Center University of Tsukuba 250 2001 Tsukuba, Japan
Centro di adroterapia oculare 60 2002 Catania, Italy
Wanjie Proton Therapy Center 230 2004 Zibo, China
Proton Therapy Center, Korea National Cancer Center 230 2007 Seoul, Korea
Heidelberg Ion-Beam Therapy Center 230 2009 Heidelberg, Germany
Rinecker Proton Therapy Center 250 2009 Munich, Germany
Medipolis Proton Therapy and Research Center 235 2011 Kagoshima, Japan
Instytut Fizyki Jądrowej 60 2011 Kraków, Poland
Centro Nazionale di Adroterapia Oncologica 250 2011 Pavia, Italy
Proton Therapy Center, Prague 230 2012 Prague, Czech Republic
Westdeutsches Protonentherapiezentrum 230 2013 Essen, Germany
PTC Uniklinikum 230 2014 Dresden, Germany
Centro di Protonterapia, APSS Trento 230 2014 Trento, Italy
Shanghai Proton and Heavy Ion Center 230 2014 Shanghai, China
Centrum Cyklotronowe Bronowice 230 2015 Kraków, Poland
SMC Proton Therapy Center 230 2015 Seoul, Korea
Proton and Radiation Therapy Center, Linkou Chang Gung Memorial Hospital 230 2015 Taipei, Taiwan
Skandionkliniken 230 2015 Uppsala, Sweden
A. Tsyb Medical Radiological Research Centre 250 2016 Obninsk, Russia
Clinical Proton Therapy Center Dr. Berezin Medical Institute 250 2017 Saint-Petersburg, Russia
Holland Proton Therapy Center 250 2018 Delft, Netherlands
UMC Groningen Protonen Therapie Centrum 230 2018 Groningen, Netherlands
The Christie 250 2019 Manchester, UK
Danish Centre for Particle Therapy 250 2019 Aarhus, Denmark
Proton Therapy Centre Apollo Hospitals 230 2019 Chennai, India
University College London Hospitals 250 2020 London, UK
Singapore Institute of Advanced Medicine 250 2020 Singapore

( In United States )

Institution Location Year of first treatment
Loma Linda University Medical Center Loma Linda, CA 1990
Crocker Nuclear Laboratory Davis, CA 1994
Francis H. Burr Proton Center Boston, MA 2001
University of Florida Health Proton Therapy Institute-Jacksonville Jacksonville, FL 2006
University of Texas MD Anderson Cancer Center Houston, TX 2006
ProCure Proton Therapy Center of Oklahoma Oklahoma City, OK 2009
Northwestern Medicine Chicago Proton Center Warrenville, IL 2010
Roberts Proton Therapy Center Philadelphia, PA 2010
Hampton University Proton Therapy Institute Hampton, VA 2010
ProCure Proton Therapy Center Somerset, NJ 2012
SCCA Proton Therapy Center Seattle, WA 2013
Siteman Cancer Center St. Louis, MO 2013
Provision Proton Therapy Center Knoxville, TN 2014
California Protons Cancer Therapy Center San Diego, CA 2014
Ackerman Cancer Center Jacksonville, FL 2015
The Laurie Proton Therapy Center New Brunswick, NJ 2015
Texas Center for Proton Therapy Dallas Fort Worth, TX 2015
Mayo Clinic Cancer Center Phoenix, AZ 2016
Mayo Clinic Jacobson Building Rochester, MN 2015
St. Jude Red Frog Events Proton Therapy Center Memphis, TN 2015
The Marjorie and Leonard Williams Center for Proton Therapy Orlando, FL 2016
Cancer and Blood Diseases Institute Liberty Township, OH 2016
Maryland Proton Treatment Center Baltimore, MD 2016
Proton Therapy Center at University Hospitals Seidman Cancer Center Cleveland, OH 2016
Miami Cancer Institute Miami, FL 2017
Beaumont Proton Therapy Center Royal Oak, MI 2017
Emory Proton Therapy Center Atlanta, GA 2018
Provision CARES Proton Therapy Center Nashville, TN 2018
New York Proton Center New York, NY 2019
South Florida Proton Therapy Institute Delray Beach, FL 2019
UAB Proton Therapy Center Birmingham, AL 2020 (Estimated)
The University of Kansas Cancer Center Kansas City, KS 2021 (Estimated)

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